For a good introduction to ASL and using it to quantify perfusion you might like to consult the following references:
Buxton, R. B. (2002 or 2009). Introduction to Functional Magnetic Resonance Imaging: principles and Techniques. Cambridge University Press.
Tofts, P. (2003). Quantitative MRI of the brain: measuring changes caused by disease. (P. Tofts, Ed.). Wiley. http://qmri.org/
Golay, X., Hendrikse, J., & Lim, T. (2004). Perfusion Imaging Using Arterial Spin Labeling. Topics in Magnetic Resonance Imaging, 15(1), 10–27.
Buxton, R. (2005). Quantifying CBF with arterial spin labeling. Journal of magnetic resonance imaging : JMRI, 22(6), 723–726. doi:10.1002/jmri.20462
Some improvements and new features are planned for BASIL, in some cases these already exist in a beta form and may be made available on request for research purposes.
Graphical user interface providing similar functionality to oxford_asl. DONE see asl_gui (from FSL 5.0.3 onward) - still in BETA!
Partial volume correction pipleline in oxford_asl. DONE (FSL 5.0.6)
Partial volume correction for QUASAR data in quasil.
Analysis of multi-TI ASL data in epochs. This would permit variations in perfusion during a multi-TI ASL experiment to be quantified by dividing the data into a series of shorter (overlapping) epochs. This can be used for functional studies in which there is no a priori design. DONE (FSL 5.0.6)
- Extension of the kinetic model to include the effects of labelled bolus dispersion, restricted exchange of label from capillaries into tissue and the presence of pre-capilliary blood signal.